Regular use of phosphodiesterase type 5 inhibitors (PDE5Is) for erectile dysfunction was associated with increased risks of serous retinal detachment (SRD), retinal vascular occlusion (RVO), and ischemic optic neuropathy (ION) among older US men in a large observational study. PDE5Is are among the most prescribed medication classes in the US and include avanafil (Stendra), sildenafil (Viagra), tadalafil (Cialis), and vardenafil (Levitra).
Slomski A. Regular Use of Erectile Dysfunction Drugs Associated With Eye Problems. JAMA. 2022;327(21):2066. doi:10.1001/jama.2022.8995
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