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Featured Clinical Reviews

News From the JAMA Network
June 7, 2022

Regular Use of Erectile Dysfunction Drugs Associated With Eye Problems

JAMA. 2022;327(21):2066. doi:10.1001/jama.2022.8995

Regular use of phosphodiesterase type 5 inhibitors (PDE5Is) for erectile dysfunction was associated with increased risks of serous retinal detachment (SRD), retinal vascular occlusion (RVO), and ischemic optic neuropathy (ION) among older US men in a large observational study. PDE5Is are among the most prescribed medication classes in the US and include avanafil (Stendra), sildenafil (Viagra), tadalafil (Cialis), and vardenafil (Levitra).

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