In reviewing a series of gallbladder conditions I had occasion to reconsider a case of ruptured gallbladder complicating an eight months pregnancy. The rarity of this complication justifies a report for the medical literature. Rupture of the gallbladder is not an unusual condition, and every year it is reported with increased frequency. Alexander1 reported twenty perforations in a series of 1,000 cases; George2 in 1925 reported 348 cases of perforation of the gallbladder; Heuer3 reported a 25 per cent incidence of perforations in a group of seventy-four cases; Judd and Phillips4 found sixty-four perforated gallbladders in a series of 508 cases of acute and subacute cholecystitis; Steinke5 reported a 15 per cent incidence of perforations in a group of 200 acutely inflamed gallbladders. The occurrence of a spontaneous rupture of the gallbladder as a complication in the late stages of pregnancy is extremely rare. A
Stone WW. PERFORATION OF THE GALLBLADDER OCCURRING IN THE LATE STAGE OF PREGNANCY. JAMA. 1937;109(23):1903–1904. doi:10.1001/jama.1937.92780490001011a
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