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JAMA Clinical Guidelines Synopsis
July 21, 2022

Therapy for Mild to Moderate Asthma

Author Affiliations
  • 1University of Chicago, Chicago, Illinois
JAMA. 2022;328(6):575-576. doi:10.1001/jama.2022.12258

Asthma is a disease characterized by recurring, reversible airways obstruction due to underlying inflammation and bronchial hyperresponsiveness. Asthma is one of the most common chronic noncommunicable diseases, affects an estimated 260 million people globally, and is associated with significant morbidity and mortality.1 Asthma with usually mild or infrequent symptoms (50%-75% of patients with asthma) contributes to 30% to 40% of exacerbations leading to emergency care; asthma-related death may occur in persons with asthma that is usually mild.2

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