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Modern biochemistry owes its results to the achievements of those men who made it a life's calling to work with material of such limited amount that it caused the development of analytic methods previously unknown. Pregl, the eye surgeon and physiologic chemist whose prime interest was directed toward sterol chemistry long before hormones became by-words, gave us organic micro-analysis. Behrens, Emich, Molisch and the American Chamot laid the foundation for inorganic microanalytic procedures. However, biologic research is more and more concerned with the determination of biologically active substances present in the living organism in infinitely small amounts. It remained for Fritz Feigl to present to the scientific worker a reference book for the qualitative analysis of smallest amounts by his "spot tests." Janet W. Matthews must be congratulated for the difficult task of translating a technical book which in its original is difficult reading even for those acquainted with German.
Qualitative Analysis by Spot Tests: Inorganic and Organic Applications. JAMA. 1938;110(4):310–311. doi:10.1001/jama.1938.02790040064029
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