In a survey of the literature, Archambault and Fromm1 were able to cull 400 cases of progressive facial hemiatrophy up to the year 1932. Of this total there were about twenty-four instances of an associated atrophy involving one side of the body. Since that time a further search of the literature reveals approximately ten more cases of "true" unilateral atrophy not due to or associated with other diseases of the central nervous system. In a consideration of unilateral atrophy, the cases occurring in association with infantile cerebral hemiplegia must be definitely excluded.2 It is possible that such hemiatrophy may be due to disuse or, in the light of recent knowledge, to the effect of the higher nerve centers and their pathways on the nutritional influences of the tissues they supply. The cause of unilateral atrophy, beginning as it usually does with facial hemiatrophy, must be identical with the
Finesilver B, Rosow HM. TOTAL HEMIATROPHY. JAMA. 1938;110(5):366–368. doi:10.1001/jama.1938.62790050004010b
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: