The past few years have witnessed the introduction into clinical medicine of an elaboration and intensification of the methods of administering oxygen-rich atmospheres for the amelioration of various diseases. Many workers and investigators in this field have published reports of their observations with results, for the most part, indicating the good effects of this method.
There is, however, some difference of opinion as to the degree of improvement to be expected from the use of oxygen, just which physiologic mechanisms it alters or modifies, and in which clinical conditions it is indicated. Certain claims for the efficacy of oxygen therapy may be considered unduly enthusiastic, even bordering on the extravagant—as is, unfortunately, so frequent an occurrence in the introduction of new or modified methods of therapy in clinical medicine. Conversely, certain reports may be accused of minimizing or disparaging its good effects.
In the present series of papers, an endeavor
HAMBURGER WW, KATZ LN, COHN DJ, RUBINFELD SH. OBSERVATIONS ON THE EFFECTS OF OXYGEN THERAPY: I. CLINICAL OBSERVATIONS IN HEART DISEASE. JAMA. 1932;98(21):1779–1783. doi:10.1001/jama.1932.02730470001001
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