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The effects of medication on epileptic seizures have been described, perhaps redundantly. In many instances a diminished number of attacks or lessened severity has constituted proof of the efficacy of a drug. Any sedative may be expected to accomplish this. To be really efficacious a drug should stop all attacks for long periods of time or, better, for the duration of its administration.
In this report a study is made to determine the number of cases in which all attacks have been stopped for the duration of treatment with sodium bromide and the duration and character of remissions brought about when attacks occurred at times during the period of treatment.
All private patients suffering for a period of more than four months from a convulsive disorder who reported to me at regular intervals during the year of January 1936-January 1937 have been selected as a group for study. There were
POLLOCK LJ. REMISSIONS OF ATTACKS IN EPILEPSY TREATED WITH SODIUM BROMIDE. JAMA. 1938;110(9):632–634. doi:10.1001/jama.1938.02790090014005
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