This case is reported to call attention to a medicament which has not been previously reported as capable of producing a contact dermatitis when applied to the skin.
A man, aged 23, a college student, complained of itching and pain in the perianal region and marked moisture in this area, Nov. 14, 1933. Local examination revealed an extensive swelling of the skin in the intergluteal, perineal and scrotal areas, with superimposed vesicles and bullae of varying size. The remainder of the physical examination was essentially negative.
The history revealed that the patient had been applying a patented remedy, "Dorb's Pile Ointment," for a period of one week for the relief of a prolapsed hemorrhoid. Two days after the ointment was discontinued the area between the buttocks began to itch and become moist.
A diagnosis of contact dermatitis was made. With rest and local applications of wet dressings the entire condition
Grolnick M. DERMATITIS DUE TO HEMORRHOIDAL OINTMENT CONTAINING KRAMERIA AND OIL OF CADE. JAMA. 1938;110(13):951–952. doi:10.1001/jama.1938.62790130001005
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