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June 18, 1932


JAMA. 1932;98(25):2222-2223. doi:10.1001/jama.1932.02730510048019

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Research on Microbic Polymorphism  The question of microbic polymorphism continues to have great interest for biologists, and particularly the study of filtrable types of micro-organisms. The optical laboratory of Professor Fabry has succeeded, it seems, in manufacturing such powerful apparatus that the investigator is enabled to observe the presence of frankly visible granulations, by means of a special form of illumination, in cultures filtered through the most dense candles under heavy pressure. These researches will soon be published. Mr. Hauduroy has described an evolutional cycle of Bacterium typhosum. Under the action of the d'Herelle bacteriophage, the bacilli of typhoid and paratyphoid are capable of assuming invisible filtrable forms. These are found in some typhoid patients, either in the blood at the beginning of the infection or in the stools at the termination of the disease. They provoke certain septicemias, in which it appears that the normal form of the bacillus

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