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May 7, 1938

Primary Carcinoma of the Lung

JAMA. 1938;110(19):1625. doi:10.1001/jama.1938.02790190095032

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This is a good review of the present knowledge of carcinoma of the lung. The writer has assembled the more important publications on the subject and added a few cases of his own. The author devotes thirty pages to the incidence of primary carcinoma of the lung, with the conclusion that the disease has increased both absolutely and relatively. The etiology of cancer of the lung is discussed in forty pages. The majority of workers have found no single etiologic agent but numerous forms of chronic irritation which cause epithelial metaplasia and malignant conditions. There are thirty pages on pathology. The histologic types are divided into (1) adenocarcinoma, (2) squamous cell, and (3) undifferentiated round and spindle cell, in accordance with the important contribution of Arkin and Wagner in The Journal, Feb. 22, 1936. The table of these two authors is reproduced, giving the histologic type and site of metastases

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