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May 14, 1938

Das Arsenvorkommen bei Reichenstein und die sog. Reichensteiner Krankheit

JAMA. 1938;110(20):1700. doi:10.1001/jama.1938.02790200068035

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This little booklet is largely now a historical and toxicologic document, owing to the fact that for the last nine years development of a pure water supply has caused the disappearance of the "reichenstein sickness," which, it came to be known, was nothing more or less than arsenical poisoning, of which many cases occurred in this region owing to the arsenic contamination of the drinking water as well as to occupational exposure to arsenic-containing ore. In addition to the usually described symptoms of chronic arsenical poisoning, it is of particular interest to note the frequency with which malignant neoplasms developed from arsenical warts, one local physician asserting that half of all the patients suffering severely from the Reichenstein sickness died of carcinoma.

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