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May 28, 1938

INTRA-ABDOMINAL CRYPTORCHIDISM TREATED WITH GONADOTROPIC SUBSTANCEV. OBSERVATIONS IN A SERIES OF TWELVE PREPUBERAL BOYS

JAMA. 1938;110(22):1799-1802. doi:10.1001/jama.1938.02790220001001
Abstract

In several previous reports I indicated the definite and distinct value of treatment with gonadotropic substance for prepuberal boys presenting genital underdevelopment in the form either of hypoplasia or of cryptorchidism or of both. It has been indicated that, as a result of employing endocrine therapy, hypoplastic genitals can be stimulated to apparent normality or even to the point of hypertrophy and also that testes situated in the inguinal canal can be developed, caused to descend and made to anchor in the scrotum.1

Hypoplasia and inguinal cryptorchidism are not the only types of genital underdevelopment that are encountered and that require correction. In the course of my experience I have encountered a number of cases of the more severe type of genital underdevelopment, in which there was an apparent absence of one or both testicles from the scrotum or inguinal canal. In these cases, to be referred to hereafter

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