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June 4, 1938


JAMA. 1938;110(23):1900-1905. doi:10.1001/jama.1938.02790230016008

The utilization of opaque substances in the diagnosis of disorders of the breast has been the subject of several enthusiastic reports in the recent literature. Hicken and his co-workers1 have reported 350 injections of the lactiferous ducts for diagnostic purposes with only two mishaps; namely, multiple abscesses of the breast following injections in the presence of acute mastitis. Their study led them to conclude that mammography is both efficient and safe.

Hicken compares the use of colloidal thorium dioxide, lipoiodine-Ciba, hippuran (Mallinckrodt), diodrast (Winthrop), bismuth oxychloride (Mallinckrodt), 15 per cent sodium iodide, and air. He believes that colloidal thorium dioxide is the least irritating and most suitable because its fluidity permits the filling of the smallest lacteal ducts and acini and yet it is of sufficient density to cast satisfactory shadows.

The technic recommended is as follows:

The breast is thoroughly cleansed as for any surgical procedure. Gentle massage

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