Physicians are all aware of the great progress in knowledge concerning tuberculosis which has occurred since the discovery of the tubercle bacillus in 1882. This, combined with the further recognized fact that there has occurred a notable decrease in the mortality and morbidity from tuberculosis in the greater part of the civilized world, has led to a feeling of satisfaction which is based on the assumption that the problems of this disease have been solved and that, in consequence, tuberculosis is in a fair way to be under definite and permanent control.
A critical analysis of the situation, however, reveals the somewhat disconcerting fact that while the very extensive researches have undoubtedly greatly increased knowledge, they have at the same time raised up many previously unsuspected problems concerning which there exist uncertainty and wide differences of opinion.
As some of the still unsolved problems concern the fundamental concepts of the
MILLER JA. SOME UNSOLVED PROBLEMS OF TUBERCULOSIS. JAMA. 1938;111(2):111–117. doi:10.1001/jama.1938.02790280001001
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