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August 6, 1938


JAMA. 1938;111(6):555-556. doi:10.1001/jama.1938.02790320067026

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To the Editor:—  In the interests of accuracy I am moved to take exception to the following statements, implications and omissions noted in the article on "The Therapy of Goiter and of Hyperthyroidism" by Drs. Bernard Fantus and Lindon Seed (The Journal, June 4):

  1. In discussing the therapy of nontoxic diffuse goiter, the iodine content of iodized salt is mentioned as 1 mg. of iodide per kilogram of salt. This appears to be an error (perhaps a typographic one) as this concentration equals one part per million, whereas the usual concentration recommended in endemic goiter areas is one or two parts of iodide per hundred thousand.

  2. In discussing the treatment of toxic nodular goiter it is stated unequivocally that iodide is contraindicated. This is a point concerning which there is a considerable difference of opinion. There are undoubtedly many cases of toxic nodular goiter which respond to iodine

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