The incidence of primary syphilis in the human breast is relatively rare. Buckley1 in 1894 reported that 12.5 per cent of the extragenital lesions occur in the breast. In 1897, Fournier2 found that the percentage was 5.1 and that only 5 per cent of the lesions occurred in the male breast.
Syphilis of the breast may manifest itself in any of the three classic stages; namely, primary (chancre), secondary and tertiary (gumma) lesions. These entities are amply described by Gravagna,3 Deaver and McFarland4 and others.5
The rarity of the condition and the problem in diagnosis that this case presented prompted the following case report:
A white man, aged 72, presented himself at the clinic with a complaint of "sore nipple" on the left side. Six weeks previously (March 29, 1923) he had been injured at this site during sexual intercourse, in a house of ill
Menville JG. CHANCRE OF THE MALE BREAST SIMULATING PAGET'S CANCER OF THE NIPPLE. JAMA. 1932;99(5):381–383. doi:10.1001/jama.1932.27410570001008
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