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Research Letter
Climate Change and Health
August 29, 2024

Greenhouse Gas Emissions and Costs of Inhaler Devices in the US

Author Affiliations
  • 1Division of Pulmonary, Allergy, and Critical Care Medicine, Stanford University School of Medicine, Stanford, California
  • 2School for Environment and Sustainability, University of Michigan, Ann Arbor
  • 3VA Center for Clinical Management Research, Ann Arbor, Michigan
  • 4Respiratory Department, East and North Hertfordshire NHS Trust, Stevenage, United Kingdom
  • 5Pulmonary Section, VA Ann Arbor Healthcare System, Ann Arbor, Michigan
JAMA. 2024;332(12):1017-1019. doi:10.1001/jama.2024.15331

Metered-dose inhalers prescribed for asthma and chronic obstructive pulmonary disease contain hydrofluorocarbon propellants, potent greenhouse gases that trap heat in the atmosphere thousands of times more powerfully than carbon dioxide. In England, these inhalers contribute an estimated 0.8 million metric tons (MMT) of annual carbon dioxide equivalent (CO2e) emissions,1 equivalent to 157 885 US homes’ yearly electricity use.2 In response, the National Health Service (NHS) has encouraged switching from propellant-containing metered-dose inhalers to propellant-free alternatives such as dry-powder and soft-mist inhalers.1

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