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August 6, 1932


JAMA. 1932;99(6):489-490. doi:10.1001/jama.1932.02740580057022

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Blood Transfusion in Sepsis  In a series of addresses before the Vienna Medizinisches Doktoren Collegium, Prof. Dr. Falta discussed the problem of blood transfusion in sepsis. The indications for this intervention have been extended in recent years. In two classes of disease, blood transfusion has been found to be especially valuable: (1) in the various forms of anemia and (2) in infectious diseases. To the first group belong anemia resulting from hemorrhages due to injuries, childbirth, ulcers, shock, anemia associated with chronic hemorrhages (as in hemorrhoids, hemophilia, hemorrhagic diathesis), and the secondary anemias associated with disturbances of nutrition and intoxications, pernicious anemia and conditions attending hemolytic icterus. The second large group comprises the infectious diseases and septic conditions. The effects of blood transfusion in these various diseases are not uniform. In the case of severe hemorrhage, transfusion constitutes "substitution therapy," since the freshly introduced blood takes over the function of

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