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October 1, 1938

The Synovial Membrane and the Synovial Fluid with Special Reference to Arthritis and Injuries of the Joints

JAMA. 1938;111(14):1320. doi:10.1001/jama.1938.02790400066027

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Few medical schools give instruction on the diagnostic and prognostic value of synovial fluid, in contrast to the emphasis placed on the cerebrospinal fluid. With the publication of Kling's readable monograph there is no longer any excuse for omitting consideration of the synovial fluid as actually and potentially as important as the spinal fluid. The present knowledge of the histogenesis, morphology and functions of the synovial membrane and its physiology are ably reviewed. The author has himself been one of the principal investigators in the field. Also the pathologic alterations of the synovial membrane in disease are discussed. This consideration of the synovial membrane is a necessary preliminary to accurate knowledge of the origin and function of synovial fluid and meaning of changes in this fluid as a reflection of the pathologic conditions. The monograph closes with four brief chapters on the clinical value of the aspiration of joint effusions

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