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November 12, 1938


Author Affiliations

London, England.

JAMA. 1938;111(20):1866. doi:10.1001/jama.1938.02790460060020

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To the Editor:—  All those who are seeking to clarify the position with regard to human requirements for vitamin B1 will appreciate Dr. Cowgill's timely and comprehensive summary.Recent work from all quarters has tended to confirm Dr. Cowgill's original suggestion of 300 international units as a basal protective level for an "average man" weighing 70 Kg. who consumes 3,000 calories a day, and it would seem clear that additions to this must be expected for normal good health and in all conditions in which there is increased metabolism.The 1935 publication of the Technical Commission of the League of Nations Health Committee, in which from 150 to 250 international units of vitamin B1 was recommended as the requirement for pregnancy and lactation, naturally obtained widespread publicity, and Dr. Cowgill rightly points out that "such a recommendation seems altogether too low." The commission's attention has frequently been called to

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