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The ninth annual report of the British Empire Cancer Campaign points out the trend toward a biologic view of the nature of cancer—the gene nutation theory. The work on cancer antiserum has excited considerable interest. Dr. Lumsden and his co-workers have succeeded in separating the euglobulin fraction of an anticancer serum from sheep ten times more effective in destroying cancer cells than the serum from which it is derived. Injections into implanted mouse tumors produced destruction of the tumor and absorption of the cells, and cancer immunity followed (autovaccination). Similar treatment of spontaneous tumors seems promising. Undestroyed portions of the tumor were removed and implanted elsewhere. If the autoplasts failed to grow the mouse became resistant, so that cancer cells were both prevented from growing and were destroyed. In a control group treated with normal sheep serum the tumors were not affected. Dr. Lumsden states that two curative
LONDON. JAMA. 1932;99(10):842–843. doi:10.1001/jama.1932.02740620052020
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