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September 10, 1932


Author Affiliations


From the John McCormick Institute for Infectious Diseases.

JAMA. 1932;99(11):909-912. doi:10.1001/jama.1932.02740630035009

It was thought that it might be profitable to study the records of serum disease as observed in the Durand Hospital since its establishment, nineteen years ago, and to discuss in a brief manner some of the pertinent questions.

FREQUENCY  Of the 2,859 patients who received diphtheria antitoxin, 804, or 28.1 per cent, showed serum reactions; of the 876 patients who received scarlet fever antitoxin 198, or 22.7 per cent, showed reactions, and of the 55 patients who received antimeningococcus serum 45, or 81.8 per cent, showed reactions. These figures do not include all of those who received serum but only those patients who were observed for ten days or longer; those who died before ten days or were discharged before that time are not included in the series.The incidence of serum disease has varied in different reports, and the statistics from hospitals in which considerable numbers of cases