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The author of this monograph studied the cerebrospinal fluid of dementia paralytica, with especial reference to possible changes in the fluid after treatment with malaria. The study included determinations of the refractometric index, electrical conductivity, chlorides, sugar, nitrogen, protein, and the Wassermann and Sachs-Georgi tests, with comparative determinations on whole blood and blood serum. He found that the refractometric index of the cerebrospinal fluid in patients treated by malaria was lower than in untreated patients. The electrical conductivity, however, did not show any difference. The chlorides in the fluid of both treated and untreated patients with dementia paralytica were the same but were lower than in normal persons. The sugar in both treated and untreated patients was no different than in normal persons. However, during the malarial injections the blood and cerebrospinal fluid sugar were increased. The nitrogen content showed no change. The total protein in untreated patients with dementia
Liquorstudien bei progressiver Paralyse mit besonderer Berücksichtigung der Veränderungen während der Impfmalaria. Inaugural-Dissertation zur Erlangung der medizinischen Doktorwürde mit Genehmigung der weiterfahrenen medizinischen Fakultät der Universität Upsala vorgelegt. JAMA. 1932;99(13):1108. doi:10.1001/jama.1932.02740650066038
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