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February 11, 1939

TREATMENT OF THE PSYCHOSES WITH INDUCED HYPOGLYCEMIA AND CONVULSIONS

JAMA. 1939;112(6):496-500. doi:10.1001/jama.1939.02800060012003
Abstract

In this paper we present our results with the hypoglycemic treatment of seventy patients with schizophrenic reactions. We have selected this group because it constitutes our first year's experience (October 1936 to October 1937) and because it offers an opportunity for consideration of the late as well as the immediate results of treatment. In addition, we report our experience with the use of metrazol for twenty-one patients with depressive psychoses. We have used metrazol for schizophrenic patients in a variety of combinations with insulin which we shall describe; however, in this paper we are placing chief emphasis on the employment of metrazol as a pharmacologic adjunct in the depressions.

HYPOGLYCEMIC METHOD  During the first year in which we utilized the hypoglycemic method seventy patients satisfactorily completed an adequate period of treatment. As we reported last year,1 there were two deaths in the course of treatment, but there have been

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