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May 23, 1953


JAMA. 1953;152(4):353. doi:10.1001/jama.1953.03690040057021

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Hazards of "Improved" Flour.  —A report of a case in the Lancet (1:577, 1953) records a syndrome of eczema, mental depression, and anorexia "associated with ingestion of chemically treated flour." The patient is a housewife, aged 50, with no personal or family history of allergic disorders, who has been under constant medical care since 1940 because of a chronic symmetrical eruption subject to acute irregular exacerbations, involving the hands, wrists, face, and neck. In March, 1952, it was noticed that contact with flour exacerbated the condition. Investigations were then carried out, using loaves made as follows: (a) by a special aeration process from flour that was entirely untreated with chemicals, the flour being mixed in stainless steel containers and fermented in aluminum bowls; (b) by the same process, except that a small quantity of edible fat was used and the dough was made in mild steel pans. The flour

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