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June 27, 1953

Familial Nonreaginic Food-Allergy.

JAMA. 1953;152(9):878. doi:10.1001/jama.1953.03690090102038

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This book presents the concept of a form of allergy that the author claims affects more than 90% of the population. He calls this idioblapsis, or familial nonreaginic food allergy. The presence of such allergy is suspected with a history of any of the following symptoms: headache, heartburn, indigestion, constipation, nervousness, neuralgia, abnormal tiredness, and hemorrhoids. Most cases of idioblaptic allergy are caused by foods, although a large percentage are caused by sensitivity to tobacco and house dust. It is inferred that such food allergy is involved, either as a direct or predisposing cause, in hypertension, epilepsy, glaucoma, dementia precox, frigidity, nausea and vomiting of pregnancy, multiple sclerosis, carcinoma of the breast, and colds. In discussing other infections, the author alludes to "the importance of idioblaptic allergy as a predisposing influence in poliomyelitis." He says elsewhere: "Among a group of 297 persons affected with clinically malignant tumor of the breast,

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