Ordinarily the diagnosis of acute gonorrhea presents few great difficulties. In the chronic forms, however, and when the infection is located extragenitally, prompt and accurate diagnosis is sometimes not so easy. Early and accurate identification is important not only from the point of view of treatment but also in the control of the disease.
One of the most satisfactory additions to diagnostic methods is the use of culture mediums in the determination of the presence of gonococci in chronic or atypical lesions. Recent experience with this procedure seems to indicate that the best method of culturing the gonococcus so far devised is by the use of a chocolate agar incubated in air containing 8 per cent carbon dioxide as described by McLeod and his co-workers1 with or without the help of the oxydase reaction or slight modifications of this technic. Using a variation of McLeod's procedure with a chocolate
DIAGNOSIS OF GONORRHEA BY CULTURE. JAMA. 1939;112(12):1158. doi:10.1001/jama.1939.02800120044013
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