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March 25, 1939

INVESTIGATIONS ON ANTIBODIES

Author Affiliations

Chicago. Department of Physiology, University of Chicago.

JAMA. 1939;112(12):1181-1182. doi:10.1001/jama.1939.02800120067025

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Abstract

To the Editor:—  What does the writer of the editorial mean when he says in "Recent Investigations on Antibodies" (The Journal, February 25, p. 735): "The investigators, however, have for the first time applied quantitative immunochemical technics to the problem of splenic immunity." Does he not consider the technics of Hektoen and Carlson quantitative or my work, using such methods, qualitative? Has he seen my "A Study of the Origin of the Immune Bodies by the Method of Organ Transplantation" (Proc. Soc. Exper. Biol. & Med.7:122-124, 1910)? Or, more to the point, because more physiologic, has the writer of the editorial read the work (confirmed later by Preston Kyes using intermediate dilutions) entitled "The Relation of the Spleen to the Fixation of Antigens and the Production of Immune Bodies" by Luckhardt and Becht, Am. J. Physiol.28:257-274 [Aug. 1] 1911)?In these papers the spleen is shown

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