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March 25, 1939

La tuberculose pulmonaire chez les sujets apparemment sains et la vaccination anti-tuberculeuse

JAMA. 1939;112(12):1190. doi:10.1001/jama.1939.02800120076033

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This monograph contains some of the most modern and most needed teaching in tuberculosis literature. It may be compared to the back of a tapestry that is rarely ever seen. Sayé has turned the tuberculosis tapestry around so that the unseen side comes into better view. An extensive review of the literature interspersed with his own results makes up this report.

Tuberculosis in those apparently well is the seed from which an important part of clinical disease emanates and constitutes the unseen source of the disease that is the greatest barrier in the way of control and eradication. While all tuberculosis arises from an exposure to some open case, those who are exposed to known open cases present from five to six times as much clinical disease as is found in the general population. In one of the author's series 18 per cent of such cases were open. This introduction

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