Among the more rare types of inflammatory lesions in the chronic cystitis group is the proliferative lesion which presents sufficient vesical manifestation to warrant a careful report of the cystoscopic and microscopic observations. It is of general clinical interest, owing to the fact that hematuria is so outstanding.
In cystitis follicularis the mucosa of the bladder is studded with nodules of various sizes, containing lymph follicles with germinal centers. Hinman and his associates1 gave an excellent description of these proliferative lesions and divided them into six groups: granular, glandular, follicular, cystic and emphysematous cystitis and bullous edema. Prior to this classification little attempt had been made to group properly these unusual lesions of the bladder. Livermore,2 quoting White and Martin, classified these epithelial cysts clinically as large and small. He reported a case in which the cyst had assumed a rather large size. Despite Hinman's1 broad
STIRLING WC. CYSTITIS FOLLICULARIS: WITH A DISCUSSION OF THE OTHER PROLIFERATIVE LESIONS OF THE BLADDER AND REPORT OF FOUR CASES. JAMA. 1939;112(14):1326–1331. doi:https://doi.org/10.1001/jama.1939.02800140024008
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