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July 18, 1953

Practical Clinical Chemistry: A Guide for Technicians.

JAMA. 1953;152(12):1182. doi:10.1001/jama.1953.03690120098034

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This book is well written, and the style is simple enough so that even the technician untutored in chemistry may easily use it. An outline for each procedure follows a comprehensive narration and explanation of the principles and techniques involved. These outlines are reprinted on detachable, perforated sheets at the back of the book for the convenience of the technician.

The selection of methods is generally excellent. The only controversial method is that for the estimation of nonprotein nitrogen of blood. The hypobromite deamination method presented is certainly simpler than the old micro-Kjeldahl method, but there is much contradictory literature concerning it, and at least one researcher reports yields as low as 78% of the true nonprotein nitrogen content with the hypobromite deamination method. The author has selected many methods that require the use of a spectrophotometer. For some time, spectrophotometers have been within the economic reach of analytical laboratories;

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