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December 17, 1949

The Case of Augustus d'Esté

JAMA. 1949;141(16):1194. doi:10.1001/jama.1949.02910160084029

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This unusual book reports the infancy and adolescence of a young man with important family connections, an illegitimate grandson of George III, who had disseminated sclerosis and who kept a careful record of his life and his illness. The record covers the early 1800's and gives a fine picture of the difficulties of medical practice with such patients in those days, difficulties which incidentally still prevail. The patient suffered from the disease for twenty-six years. The book has special attraction for neurologists with an interest in medical history.

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