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December 31, 1949


JAMA. 1949;141(18):1319. doi:10.1001/jama.1949.02910180047016

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To the Editor:—  I should like to report another case of black hairy tongue which apparently resulted from oral administration of penicillin troches. Mrs. H. H. D., age 58, was seen Oct. 21, 1949 with a chief complaint of sore throat and feverishness for forty-eight hours. The physical examination revealed moderate pharyngitis and oral temperature of 100 F. but no other significant physical findings.Medication consisted of penicillin troches, 50,000 units every three hours during waking hours, and acetylsalicylic acid, 1 tablet when required for discomfort. Three days later, after having taken 18 troches, the patient returned for check-up. The throat and temperature were normal. The tongue was noted to be normal in color. Six days later, the patient stated by telephone that after her previous return visit, sore throat had again developed and that she had purchased 24 penicillin troches and had used them according to previous directions. After

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