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April 29, 1939

REMOVAL OF THE THYMUS: SURGICAL VERSUS ROENTGEN RAY EXTIRPATION

Author Affiliations

SALT LAKE CITY

From the Department of Anatomy of the University of Utah School of Medicine.

JAMA. 1939;112(17):1680-1682. doi:10.1001/jama.1939.02800170026008
Abstract

In a series of recent articles, co-authors Shay, Gershon-Cohen, Fels and the Meranzes1 have reported that roentgen ray destruction of the thymus gland in young albino rats produced a delayed development of the male testes, with resultant temporary sterility, and a hypophysial change similar histologically to that produced by castration. These changes were said to be progressive to the age of 100 days, after which reparative processes were said to be instituted which resulted in complete recovery of the testes. These observations deserve careful consideration in the light of the many negative results previously obtained by surgical extirpation of the thymus. We believe that the average clinician should be aware of the differences in effect of the two methods. It is with this fact in mind that we wish to present our experimental results and views on this controversial subject.

We would assume that roentgen ray ablation of the

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