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January 14, 1950

Pharmacology and Toxicology of Uranium Compounds with a Section on the Pharmacology and Toxicology of Fluorine and Hydrogen Fluoride

JAMA. 1950;142(2):140. doi:10.1001/jama.1950.02910200068028

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Until the present development of atomic energy, uranium and its compounds were of minor interest in medicine. Now, however, this element has assumed basic importance in all work connected with nuclear fission by chain reacting piles, and hence its pharmacology and toxicology have been under intensive study. The reports presented in the volumes herein reviewed should be important reference tools to medical workers in the atomic energy field.

The research reported in these volumes, conducted principally at the University of Rochester, is of a high order and was undertaken to solve a number of immediate problems which arose as by-products of the development of the atomic bomb. The introduction to these reports summarizes briefly but adequately the principal conclusions to be derived from the detailed discussions which follow. The chemistry of the uranium compounds is next discussed, since an appreciation of this subject is necessary in order to evaluate the

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