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January 28, 1950

The Therapeutic Value of Streptomycin: A Study of 3,000 Cases

JAMA. 1950;142(4):295. doi:10.1001/jama.1950.02910220075038

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Abstract

This volume presents the complete and exhaustive data gathered by the Committee on Chemotherapy of the Division of Medical Sciences of the National Research Council during the course of investigations which they sponsored on the therapeutic value of streptomycin. The work was started early in 1946, at a time when streptomycin was limited in supply and its extent of usefulness relatively unknown. Over a six month period, data on nearly 3,000 patients was collected, and this volume presents a critical analysis of these cases.

Because of the short supply of the drug and because of other investigations already under way, the effect of streptomycin in tuberculosis was not included as part of the investigative program. However, the other uses of streptomycin are adequately covered.

The data are arranged according to organ systems affected except for such diseases as tularemia, typhoid and brucellosis, which are discussed in separate chapters. Toxic reactions

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