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May 13, 1939

Current Comment

JAMA. 1939;112(19):1970-1971. doi:10.1001/jama.1939.02800190084020

SEX HORMONES HOLD THE STAGE  Today the desks of physicians are being flooded again with fantastic advertising claims for sex hormones. New heights have been reached with the publication of two pamphlets, "Perandren" (Ciba) and "Roche Review" (Roche-Organon). The recommendations reveal a policy with little regard for scientific evidence. The name of one of the Roche-Organon preparations, Neo-Hombreol (presumably new manhood oil), is significantly reminiscent of "Lost Manhood" exploitation. And most of the claims are apparently based on one or two experiences in which the reporter has neglected to discount for the power of suggestion. Ciba naively advises testosterone propionate for therapy on the basis of admitted "bits of evidence, published and unpublished." "Atonicity" and "mammary gland pathologies" are among the firm's recommended indications for androgenic therapy. But this is conservatism itself when compared to the opus of the "scientific staff" of Roche-Organon, who have prepared a chart and "dosage