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This monograph contains a detailed analysis of the changes that occur in placentas of syphilitic babies. The study is based on thirty-nine cases of syphilis observed by the author. The results indicate that the average weight of the placenta in syphilitic patients who give birth to full term babies is not greater than that in nonsyphilitic cases. In premature labors there seems to be an increase in weight of the placenta, though this is not definite. The increase in the ratio between the placenta and the fetus in syphilis is due to the frequency of premature labor and to the frequent occurrence of fetal death in utero. Histologically, aside from the occurrence of spirochetes, placentas in syphilitic patients do not show any changes that cannot be found in other placentas. However, these abnormalities are to be found much more commonly in syphilis than otherwise. Therefore, when a placenta shows at
Studien über die Veränderungen der Nachgeburt bei Lues. JAMA. 1932;99(18):1535. doi:10.1001/jama.1932.02740700075039
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