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May 20, 1939

Scarlet Fever

JAMA. 1939;112(20):2087. doi:10.1001/jama.1939.02800200085026

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Containing a concise account of the application of the investigations of the authors to the prevention and treatment of scarlet fever, this book summarizes their articles on these matters during the past twenty years or more. The demonstration by human experiments on the part of the authors that scarlet fever may be caused by hemolytic streptococci was followed by the discovery of a specific streptococcic scarlet fever toxin, which in turn led to the Dick test for susceptibility to scarlet fever, to successful active immunization against scarlet fever and to the use in treatment of a specific antitoxin. The book describes the practical use of these measures and the results obtainable. The preparation of the scarlet fever toxin and the technic of testing its potency are described in detail. The book is a landmark in the history of scarlet fever.

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