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October 24, 1953


JAMA. 1953;153(8):723-725. doi:10.1001/jama.1953.02940250029008


REPORT OF A CASE  John L. Dadey, M.D. and A. G. Kammer, M.D., PittsburghChlordane is a recently developed insecticide with the empiric formula C10H6Cl8. This chlorinated hydrocarbon is said to be 1,2,4,5,6,7,8,8-octachloro 2,3,3a, 4,7,7a-hexahydro 4,7-methanoindene, with the structural formula shown in figure 1.The commercially available technical product is not a pure substance, but contains in addition to chlordane some five or six closely related compounds whose respective proportions may vary.1 The formulations of technical chlordane include oil solutions, emulsions, dusts, and wettable powders. These find extensive use in the eradication of such household pests as flies, cockroaches, fleas, and mosquitoes as well as agricultural crop enemies such as grasshoppers and certain beetles. Because of the widespread domestic, industrial, and agricultural distribution of the various preparations of chlordane, cases of accidental poisoning may be expected from time to time. These should

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