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October 5, 1946


JAMA. 1946;132(5):304. doi:10.1001/jama.1946.02870400052020

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To the Editor:—  In an editorial with this title in The Journal, July 6, you reviewed the most interesting work of Dr. Woolley and his associates on their discovery of new nonidentified nutritional substance for bacteria in certain protein materials.Apparently Dr. Woolley has not been aware of the fact that my collaborator, Dr. Freedman, and I were very much on the same subject in the years 1920-1923. As a matter of record, the same subject was the basis of Dr. Louis Freedman's thesis in Columbia University College of Physicians and Surgeons in 1922. Aside from these facts a difference of conception is apparent between our early work and that of Dr. Woolley, which is well worth recording.While Dr. Woolley is of the opinion that strepogenin is an integral part of certain proteins, our conception on the contrary was (Nutritional Factors in the Growth of Yeasts and Bacteria: I.

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