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May 27, 1939

SULFANILAMIDE IN ACTINOMYCOSIS

Author Affiliations

Denver From St. Joseph's Hospital, St. Joseph, Mo.

JAMA. 1939;112(21):2190. doi:10.1001/jama.1939.02800210084023

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Abstract

To the Editor:—  I should like to add corroboration to the results of Miller and Fell with sulfanilamide in actinomycosis (The Journal, February 25, p. 731).On Feb. 12, 1937, I made a pathologic examination of two fallopian tubes and portions of two ovaries removed from a married woman aged 20. Smears and histologic sections indicated extensive actinomycotic infection. The operation was performed for nonspecific pelvic inflammation of six weeks' duration. It was an unsatisfactory operation owing to extensive adhesions and evident inflammatory activity. The pelvis showed gross evidence of infectious contamination. Convalescence was delayed and followed by a gradually increasing pelvic induration and mass formation associated with a low grade temperature. Potassium iodide and other medication were given without relief. High voltage roentgen therapy was suggested and refused. By this time the general condition of the patient was grave. On a purely empiric basis sulfanilamide was administered in regular,

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