[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 34.238.190.122. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Other Articles
May 27, 1939

USE OF SODIUM DIPHENYL HYDANTOINATE AS ANTICONVULSANT

Author Affiliations

Harvard Medical School Boston

JAMA. 1939;112(21):2190. doi:10.1001/jama.1939.02800210084024

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.

Abstract

To the Editor:—  It is gratifying to see Dr. Kimball's report testifying to the effectiveness of sodium diphenyl hydantoinate as an anticonvulsant as used in his series of 152 cases since the beginning of 1938 (The Treatment of Epilepsy with Sodium Diphenyl Hydantoinate, The Journal, April 1, p. 1244).His was the first clinic to which the drug was furnished after Dr. Merritt and I had given it a ten months trial under rigid precautions in our own wards. This in turn was only after we had demonstrated its ability to prevent experimentally produced convulsions and its low toxicity in animals (Putnam, T. J., and Merritt, H. H.: Experimental Determination of the Anticonvulsant Properties of Some Phenyl Derivatives, Science85:525 [May 28] 1937).His observations are therefore of particular value. It is of course of great importance to record, as Dr. Kimball has done, any peculiar side effects which

First Page Preview View Large
First page PDF preview
First page PDF preview
×