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June 3, 1939


Author Affiliations

Douglas, Ariz.

JAMA. 1939;112(22):2275. doi:10.1001/jama.1939.62800220005010d

In 1919 a case of intestinal obstruction in a newborn infant, caused by inspissated meconium, was described by Bullowa and Brennan.1 Hughes2 described a similar case in 1922. Since then, others have described the condition; Dodd3 in 1936 reported the twenty-second case and gave a summary of the cases previously described. In six cases, including her own, necropsies revealed pathologic changes in the liver or pancreas, affecting the secretion of bile or pancreatic juice. Lack of either of these secretions was thought to be the causative factor.3 The terms "meconium ileitis" and "meconium ileus" are both used as descriptive of the condition. The latter seems more appropriate.

REPORT OF CASE  The case here reported is one of meconium ileus and, in addition, presented an ileocolic intussusception that undoubtedly had existed before birth:An infant girl was the third living child born to a healthy mother by