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November 5, 1932

Contribution à l'étude du traitement de la paralysie générale: L'impaludation cérébrale.

JAMA. 1932;99(19):1627. doi:10.1001/jama.1932.02740710071036

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The author devotes eighty pages to a description of the present and older forms of treatment of dementia paralytica. In this survey he concludes that the only really valuable therapy is that of inoculation with malaria. He says: "The treatment of dementia paralytica by means of arsenicals, bismuth, mercury, vaccines, diathermy, and so on has but few proponents. It is true that a certain number of clinicians use acetarsone; yet for the most part chemotherapy is but an adjunct of malaria therapy." This would seem to be an extreme continental and specifically French view, since acetarsone (stovarsol) is hardly ever used by any but French physicians, and many forms of treatment besides that with malaria are now in common use in the United States. There is a lengthy discussion of the technic of practically abandoned methods, such as the use of intraspinal and intraventricular and subarachnoidal injections of various medications

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