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November 14, 1953


JAMA. 1953;153(11):1040-1041. doi:10.1001/jama.1953.02940280048020

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To the Editor:—  A recent paper by Biegeleisen in the April 15, 1953, issue of the New York State Journal of Medicine describes that author's experience in the treatment of varicose veins. This report was abstracted in the Aug. 15, 1953, issue of The Journal. The author states that "in the absence of proved permanency of cure by surgical means, injection treatment remains the treatment of choice in most cases." This statement is in direct conflict with the reports from leading medical centers throughout the country and, therefore, deserves careful analysis.Recent experimental and clinical investigations have demonstrated that injection therapy is not an effective method of treatment for varicose veins. It is impossible to localize accurately the effects of a sclerosing solution. Even in expert hands, injections may produce allergic reactions, skin sloughs, and deep phlebitis. Kinmonth and Boyd state that histological studies of veins injected with sclerosants indicate

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