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March 11, 1950

SALT AND PROTEIN RESTRICTION: Effects on Blood Pressure and Renal Hemodynamics in Hypertensive Patients

Author Affiliations

New York

From the Departments of Medicine and Physiology, New York University College of Medicine.

JAMA. 1950;142(10):711-715. doi:10.1001/jama.1950.02910280019004

The abundant literature on sodium chloride restriction and dietary treatment of hypertension has recently been reviewed by Pines and Perera.1 A rice diet regimen of salt and protein restriction has been suggested 2 for the treatment of hypertensive patients. We have used this diet in the study of a limited number of patients, our attention being directed to its effects on blood pressure and renal function.

METHODS  Twelve patients with essential hypertension were selected from the Hypertension and Nephritis Clinic of the New York University Clinic and from the Third (New York University) Medical Division of Bellevue Hospital. They were chosen at random from patients with hypertensive disease of varying extent and duration.Blood pressure was determined by the auscultatory method with a mercury sphygmomanometer. A group of three readings was made every morning, noon and late afternoon, after bed rest for not less than fifteen minutes, and the

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