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November 5, 1932

The Life Line of the Thyroid Gland: A Contribution to the Study of Goitre.

JAMA. 1932;99(19):1629. doi:10.1001/jama.1932.02740710073042

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In this volume, which deals mainly with the work done in the senior author's laboratory during the last three years, are traced the normal course of growth of the thyroid gland in experimental animals, and the effects on its development of various diets, iodine, sex, season, and sanitary condition. The large amount of valuable data on nutrition and dietary deficiencies which Colonel McCarrison has accumulated have been subjected to an intensive statistical scrutiny from the standpoint of goiter. The authors make the problem of goiter unnecessarily complicated by their methods of classification; for example, it is difficult to understand "the classical type of endemic goiter," "the diffuse colloid goiter of the plains," "the goiter met with in New Zealand," "childhood goiter" and "sporadic goiter" as five different types of goiter. They consider diet an important factor in the genesis of goiter; but because enlargement of the thyroid gland does not

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