My purpose in this paper is to report two cases of pigmentation—one resulting from a photosensitizing dye and the other from a toilet water—and to discuss briefly the parenteral and ingested photosensitizing substances as well as the topical photosensitizers.
Pigmentation of the skin may follow the topical application of a number of photosensitizers, e. g. eosin and eosin compounds, oil of bergamot, oil of lavender, oil of cedar, vanillin oil, perfume, eau de cologne, mercury bichloride, dyes and Dictamnus albus (gas plant).
Substances such as sulfanilamide, gold, silver, hematoporphyrin, acriflavine, eosin, rose bengal, erythrosin (fluorescein) and chlorophyll, when injected into the body, possess the property of sensitizing the skin to light.
Photosensitization in animals has been associated with the eating of buckwheat, clover and sudan grass.
REPORT OF CASES
Miss A. P., aged 30, a brunette, consulted me March 18, 1938, for three dark gray, flat, superficial, pigmented
Sandler IL. PHOTOSENSITIZING AGENTS: A BRIEF REVIEW OF THE LITERATURE. JAMA. 1939;112(23):2411–2413. doi:10.1001/jama.1939.62800230002012b
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