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The author advances a synthetic treatment of evolution on a basis of comparative embryology, comparative anatomy and a broad understanding of the mechanics of development. The theory that the struggle for existence is always associated with destruction of less viable, less well adapted persons and at times with destruction of entire populations or species is discussed. The author indicates the importance of natural selection as a factor leading toward creation of more integrated forms of organization. Differences between mobile and conserving forces of natural selection are discussed. Fundamental processes involved in the transformation of the individual organism during its historic development are related in considerable detail, and special emphasis is placed on the processes involved in the accumulation of reserves of variability from the genetic viewpoint.
The author served as director of the Institute of Evolutionary Morphology and was a member of the Academy of Sciences of the USSR until
Factors of Evolution:. The Theory of Stabilizing Selection. JAMA. 1950;142(12):949. doi:10.1001/jama.1950.02910300087029
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